Gastritis is inflammation of the stomach lining irrespective of the cause. It can be caused by a number of factors, the most common of which are long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and infection with the bacteria Helicobacter pylori. Some people have no symptoms of gastritis (asymptomatic), while others may complain of dyspepsia (indigestion) and a gnawing stomach pain. However, it should be kept in mind that not all patients who complain of such symptoms are suffering from gastritis.
What are proton pump inhibitors?
Proton pump inhibitors (PPIs) are the most effective group of drugs that inhibit gastric acid secretion in the stomach. The PPIs are the best suppressors of acid production and is one of the most widely sold drugs worldwide on account of its outstanding efficacy and safety. It may reduce as much as 90-98% of 24-hour acid secretion with standard doses.
Antacids are weak bases that neutralize the gastric acid. It is the mainstay treatment of acid-peptic disorders for long time until the arrival of H2 blockers and proton pump inhibitors. Antacids still continue to be popular nonprescription remedy among patients for the treatment of heartburn and dyspepsia.